作者: Shih-Chieh J. Huang , Alexander B. Artyukhin , Julio A. Martinez , Donald J. Sirbuly , Yinmin Wang
DOI: 10.1021/NL071641W
关键词: Amorphous silicon 、 Nanowire 、 Lipid bilayer phase behavior 、 Carbon nanotube 、 Materials science 、 Lipid bilayer 、 Analytical chemistry 、 Chemical engineering 、 Photobleaching 、 Membrane 、 Vesicle 、 Mechanical engineering 、 General Materials Science 、 Bioengineering 、 General chemistry 、 Condensed matter physics
摘要: Curved lipid membranes are ubiquitous in living systems and play an important role many biological processes. To understand how curvature composition affect membrane formation fluidity, we have assembled studied mixed 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) supported bilayers on amorphous silicon nanowires grown around carbon nanotube cores with controlled wire diameters ranging from 20 to 200 nm. We found that vesicles fused onto nanowire substrates formed continuous for all DOPC−DOPE mixtures tested (with the DOPE content of up 30%). Our measurements demonstrate nanowire-supported mobile, exhibit fast recovery after photobleaching, a low concentration defects. Lipid diffusion coefficients these high-curvature tubular comparable values reported flat increase slightly decreasing diameter. A free spac...