Acute hypermagnesemia: a rare complication of antacid administration after bone marrow transplantation.

摘要: Abstract Introduction : We reported a case of hypermagnesemia in whom hypotension, hypothermia, and coma developed after repetitive doses seemingly harmless antacid for epigastric pain following bone marrow transplantation. Methods For this case, serial electrolytes, blood urea nitrogen, creatinine, calcium, magnesium were obtained. Issues addressed the restoration normal hydration by saline, together with forced diuresis to hasten renal excretion magnesium, eventual changes its levels. Results The highest measured concentration was 5.9 mmol/l. She recovered without dialysis. patient's condition improved intravenous calcium gluconate, saline solution infusion, cardiovascular support. Conclusion Hypermagnesemia is rare allogeneic stem cell recipients receiving cyclosporine therapy prevention acute graft-vs.-host disease (GVHD). A posttransplant status possible GVHD, poor nutritional intake, impaired intestinal absorption, dehydration, use aluminum magnesia oral suspension may have resulted imbalance. This report highlights several associated nonrenal risk factors hypermagnesemia, which include gastrointestinal tract disease, concomitant medications, particularly, antacids that contain magnesium.