HMGB1: a novel protein that induced platelets active and aggregation via Toll-like receptor-4, NF-κB and cGMP dependent mechanisms.

作者: Xinyu Yang , Haichao Wang , Menmen Zhang , Jin Liu , Ben Lv

DOI: 10.1186/S13000-015-0348-3

关键词: NF-κBThrombinBiologyTLR4Platelet activationPlateletProinflammatory cytokineHMGB1PathologyExtracellular

摘要: Background Thrombotic diseases are a group of prevalent and life-threatening diseases. Selective inhibition of pathological thrombosis holds the key to treat variety of thrombotic …

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