Characterization of bacterial community shift in human Ulcerative Colitis patients revealed by Illumina based 16S rRNA gene amplicon sequencing

作者: Sandeep A Walujkar , Dhiraj P Dhotre , Nachiket P Marathe , Parimal S Lawate , Renu S Bharadwaj

DOI: 10.1186/1757-4749-6-22

关键词: Ulcerative colitisAmplicon sequencingMicrobiologyBiologyGut floraMedical microbiologyGeneParasitologyObligate anaerobe16S ribosomal RNABioinformatics

摘要: Background The healthy human intestine is represented by the presence of bacterial communities predominantly belonging to obligate anaerobes; however disparity and dysanaerobiosis in intestinal microflora may lead progression ulcerative colitis (UC). The foremost aim this study consider compare gut microbiota composition patients suffering from different stages UC.

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