Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics

作者: Deborah L. Diamond , Andrew J. Syder , Jon M. Jacobs , Christina M. Sorensen , Kathie-Anne Walters

DOI: 10.1371/JOURNAL.PPAT.1000719

关键词: BiochemistryEnergy homeostasisViral replicationProteomeLipidomeBioenergeticsGlycolysisCell biologyLipid metabolismBiologyCitric acid cycle

摘要: … the intracellular processes influenced by this virus. Our proteomic data suggest that HCV … , which favor host biosynthetic activities supporting viral replication and propagation. This is …

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