Memory T lymphocytes

摘要: Immunological memory protects organisms from recurrent challenge by pathogens. The persistence of a heightened reactive state initiated antigenic is mediated long-lived lymphocytes. survival T cells thought to require stimulation through the cell receptor (TCR), sometimes persistent antigen. However, can survive in absence antigen, which case TCR provided surface self-peptide/major histocompatibility complex (MHC) molecules and cytokines are required sustain cells. Recent work using mouse models has insights into origin Understanding mechanisms that underlie differentiation may improve effectiveness vaccines induction memory.