Pain mediation by prostaglandin E2 and leukotriene B4 in the human masseter muscle
作者： Britt Hedenberg-Magnusson , Malin Ernberg , Per Alstergren , Sigvard Kopp
DOI: 10.1080/000163501317153185
关键词: Anesthesia 、 Masseter muscle 、 Masticatory force 、 Prostaglandin E2 、 Fibromyalgia 、 Tenderness 、 Chronic pain 、 Leukotriene B4 、 myalgia 、 Medicine
摘要: The pathophysiology behind chronic pain from masticatory muscles is unclear. Our hypothesis was that this of inflammatory origin and associated with release mediators. aim study therefore to investigate the presence prostaglandin E2 (PGE2) leukotriene B4 (LTB4) in masseter muscle plasma their relation myalgia. Nineteen patients fibromyalgia, 19 local myalgia muscle, 11 healthy individuals were examined regard muscular intensity at rest pressure threshold. Inclusion criteria for least 3 months tenderness on digital palpation. Samples obtained by microdialysis, dialysates venous blood samples analyzed PGE2 LTB4 concentration. Intramuscular levels found all groups, significantly higher whom positively co...
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