Pharmacotherapy of Bipolar Disorder in Old Age: Review and Recommendations

作者: Robert C. Young , Laszlo Gyulai , Benoit H. Mulsant , Alastair Flint , John L. Beyer

DOI: 10.1097/00019442-200407000-00002

关键词: DivalproexDepression (differential diagnoses)PsychologyNeurocognitiveManiaBipolar disorderLithium (medication)Atypical antipsychoticPsychiatryPharmacotherapyGeriatrics and GerontologyPsychiatry and Mental health

摘要: The authors reviewed the evidence-base for pharmacological treatment of mania and bipolar (BP) depression in late life. Treatment benefits side effects may be modified by age-associated factors, such as neurocognitive impairments. Lithium divalproex have most often been studied elderly patients, both efficacious acute mania, but there are no controlled efficacy or effectiveness trials. role atypical antipsychotic agents remains to clarified. Similarly, systematic studies BP patients. make suggestions management delineate priorities research.

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