The effect of bariatric surgery on renal function

摘要: Abstract Background Obesity is associated with albuminuria and impaired renal function. We previously reported on 38 nondiabetics improved after Roux-en-Y gastric bypass (RYGB). Methods Our objectives were to evaluate changes in function, urinary albumin-to-creatinine ratio (UACR), glomerular filtration rate (GFR) a larger cohort of patients normal or mildly undergoing RYGB sleeve gastrectomy at 1 year postop. This was retrospective study. Inclusions: preoperative postoperative serum urine albumin creatinine weight (kg). Exclusions: preop chronic kidney disease (CKD)≥Stage 3 macroalbuminuria (UACR≥300 mg/g). Primary outcomes: UACR estimated GFR (eGFR) year. The setting public hospital New York City, 2004–2011. Results 158 met inclusion criteria; 91.8% female; mean age 40.8 years; 84.2% white Hispanic, 14.6 % black. Hypertension present 43.0%, diabetes mellitus 28.5%. 21.5±3.2 mg/g, decreasing 10.2±1.2 mg/g ( P Conclusion In this mainly female minority population, decreased within the range, while eGFR from range for Stage 2 CKD Microalbuminuria resolved most affected hyperfiltration nearly half those affected. study limited by its nature. Prospective studies should be performed.