Left atrial pressure and sodium balance in conscious dogs on a low sodium intake.

摘要: 10 conscious chronically prepared dogs were used. After recovery from thoracotomy (catheter into the left atrium, nylon purse string around mitral annulus) they kept on a low sodium intake (<0.5 meq Na/kg bw daily). On 51 days atrial pressure (LAP) was increased for 60 min about cm H2O once daily by tightening (distension period: DP). During DP urine volume ( $$\dot V$$ ) threefold, and excretion (E Na) sixfold. The amount of renal loss when LAP exceeded considerably. application DOCA (15 mg i.m.) did not diminishE Na during thereafter. heart rate 70 b/min mean arterial blood 15 mm Hg. data suggest that stimulation intrathoracic receptors reversible stenosis augments even in state highly stimulated tubular resorption.