Pancreatic stone protein as a postmortem biochemical marker for the diagnosis of sepsis

作者: Cristian Palmiere , Marc Augsburger

DOI: 10.1016/J.LEGALMED.2014.08.003

关键词: AutopsyIntensive care unitInflammationProcalcitoninBiologyIntensive careC-reactive proteinSepsisAcute-phase proteinPathology

摘要: Pancreatic stone protein/regenerating protein has recently emerged as an interesting diagnostic and prognostic marker of inflammation sepsis in the clinical field. Increased blood concentrations have been described patients with sepsis. Moreover, a high accuracy predicting fatal outcomes septic admitted to intensive care units reported. In this study, we investigated pancreatic postmortem serum series sepsis-related fatalities, local infections non-infectious cases that underwent medico-legal investigations. Procalcitonin, C-reactive protein, interleukin 6, soluble triggering receptor expressed on myeloid cells-1 were measured collected during autopsy group deaths, non-septic unit patients. Statistically significant differences observed between control A positive correlation was found procalcitonin values cases. is measurable from femoral autopsy. Additionally, field, can be used biochemical for diagnosis

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