Cervical carcinoma-associated fibroblasts are DNA diploid and do not show evidence for somatic genetic alterations.
作者： Willem Ernst Corver , Natalja Tatjana ter Haar , Gert Jan Fleuren , Jan Oosting
DOI: 10.1007/S13402-011-0061-5
关键词: Cancer research 、 Mutation 、 Biology 、 Immunohistochemistry 、 SNP array 、 Carcinogenesis 、 Vimentin 、 Somatic cell 、 Ploidy 、 Epigenetics
摘要: Background Cancer-associated fibroblasts (CAFs) have been recognized as important contributors to cancer development and progression. However, opposing evidence has published whether CAFs, in addition epigenetic, also undergo somatic genetic alterations these changes contribute carcinogenesis tumour
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