Inactivation of glutathione S-transferases by nitric oxide-derived oxidants: exploring a role for tyrosine nitration.
作者： Patrick S.-Y. Wong , Jason P. Eiserich , Sharanya Reddy , C.Leticia Lopez , Carroll E. Cross
关键词: Protein oxidation 、 Nitration 、 Tyrosine 、 Glutathione S-transferase 、 Tetranitromethane 、 Peroxynitrite 、 Glutathione 、 Biochemistry 、 Reactive nitrogen species 、 Chemistry
摘要: … residue in GSTs might be a critical target for nitration by RNS. We therefore used HPLC and … inactivated by various •NO-derived oxidants and suggest that tyrosine nitration might play a …
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