Parietal and hippocampal contribution to topokinetic and topographic memory

摘要: This paper reviews the involvement of parietal cortex and hippocampus in three kinds spatial memory tasks which all require a previously experienced movement space. The first task compared, by means positron emission tomography (PET) scan techniques, production, darkness, self-paced saccades (SAC) with reproduction, learned sequence to visual targets (SEQ). results show that bilateral increase activity was seen depth intraparietal sulcus medial superior (superior gyrus precuneus) together frontal but only SEQ task, involved possibly also motor memory. second is vestibular contingent requires subject makes, saccade remembered position target after passively imposed whole-body rotation. Deficits this involves memory, were found predominantly patients focal vascular lesions parieto-insular (vestibular) cortex, supplementary area-supplementary eye field area, prefrontal cortex. third mental navigation from route real environment (the city Orsay France). A PET study has revealed when subjects asked remember landmarks there activation middle hippocampal regions, left inferior temporal gyrus, precentral posterior cingulate gyrus. If route, their movements along dorsolateral areas, right precuneus, occipital fusiform lateral premotor area found. Subtraction between two conditions reduced activated areas hippocampus, precuneus insula. These data suggest are both dynamic aspects for name 'topokinetic memory' proposed. could overlap be different those cartographic static 'topographic'