Body Mass Index across Adolescence and Substance Use Problems in Early Adulthood

摘要: Excessive substance use and obesity are underpinned by a number of shared risk factors (e.g., reward dysfunction, impulsivity). Food drugs abuse engage similar reward-related neural circuitry the food-drug competition hypothesis proposes that excess consumption food may diminish desire for competing receptors associated with motivation. Adolescence is high-risk period both increased excessive weight gain. In present study, authors tested whether, consistent hypothesis, elevated body mass index (BMI) across adolescence predicted fewer problems in young adulthood. multiwave prospective study community sample families enriched high levels disorders, first identified BMI trajectories 565 participants using latent class growth analysis. They then used maximum likelihood methods to compare equality mean alcohol-, drug-, nicotine-related during early adulthood adolescent trajectories. Participants obese relative normal trajectory had drinking illicit drug Relative overweight trajectory, nicotine dependence was significantly higher among The current findings provide partial support which suggests highly palatable foods be rewarding enough compete transdiagnostic approaches reducing problematic overeating useful. However, relationship between requires further study. (PsycINFO Database Record