A gene-based radiation hybrid map of chicken microchromosome 14: Comparison to human and alignment to the assembled chicken sequence

作者: Mireille Morisson , Sophie Leroux , Carine Jiguet-Jiglaire , Sirine Assaf , Frédérique Pitel

DOI: 10.1186/1297-9686-37-3-229

关键词: MicrochromosomeGeneticsSequence alignmentExpressed sequence tagSyntenyNucleic acid sequenceRadiation hybrid mappingGene rearrangementBiologyGene mapping

摘要: We present a gene-based RH map of the chicken microchromosome GGA14, known to have synteny conservations with human chromosomal regions HSA16p13.3 and HSA17p11.2. Microsatellite markers from genetic were used check validity additional developed EST data yield comparative mapping data. A high rate intra-chromosomal rearrangements was detected by comparison assembled sequence. Finally, alignment sequence showed small number discordances, most which involved same region chromosome spanning between 40.5 75.9 cR6000 on map.

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