Evaluating patient-derived colorectal cancer-xenografts as preclinical models by comparison with patient clinical data
作者： Manoel Nunes , Patricia Vrignaud , Sophie Vacher , Sophie Richon , Astrid Lièvre
DOI: 10.1158/0008-5472.CAN-14-1590
关键词: Gene expression profiling 、 Cetuximab 、 Downregulation and upregulation 、 Cancer research 、 Clinical significance 、 KRAS 、 PTEN 、 Medicine 、 Neuroblastoma RAS viral oncogene homolog 、 Colorectal cancer
摘要: … PDX molecular data were compared with that published for patient colorectal tumors in The … Responses of PDXs to cetuximab recapitulate also clinical data in patients, with partial or …
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