The diversity between curatively resected pancreatic head and body-tail cancers based on the 8th edition of AJCC staging system: a multicenter cohort study.

摘要: To our knowledge, there are no studies to systematically compare the detailed clinical significance between curatively resected pancreatic head (ph) and body-tail (pbt) ductal adenocarcinoma based on new 8th edition of AJCC staging system (8th stage) that was just applied in practice 2018. Three hundred fifty-one patients with (PC) from three center hospitals were entered into this multicenter cohort study. Increasing tumor size (P < 0.001), T stage (T1 + T2 vs T3 + T4, P = 0.003), frequent postoperative liver metastasis (PLM) (P = 0.002) (IA VI, P < 0.001; I + II III + IV, P = 0.002) closely associated progression pbt cancers compared ph cancer patients. Moreover, size≥3 cm (P = 0.012), (III + IV) (P = 0.025) PLM (P = 0.010) identified as independent risk factors logistic analysis. Patients had a significantly worse overall survival (P = 0.003). an unfavorable factor multivariate analysis (P = 0.011). In addition lymph nodes metastasis, 8th stage, vascular invasion PLM, increasing advanced also poor prognosis 131 cases Ph Pbt, for PC patients, much more aggressive than according system. comprehensive sensitive reflect malignant biology cancers.