Mammalian hairy and Enhancer of Split Homolog 1 Regulates Differentiation of Retinal Neurons and Is Essential for Eye Morphogenesis

作者: Koichi Tomita , Makoto Ishibashi , Kiyoshi Nakahara , Siew-Lan Ang , Shigetada Nakanishi

DOI: 10.1016/S0896-6273(00)80093-8

关键词: RetinaRetinalTransfectionCellular differentiationHES1Eye morphogenesisMorphogenesisCell biologyBiologyGeneticsStem cell

摘要: … Retinal progenitor cells infected with HES1-transducing retrovirus did not differentiate into mature retinal cells, suggesting that persistent expression of HES1 blocks retinal development…

参考文章(51)
K. Takebayashi, Y. Sasai, Y. Sakai, T. Watanabe, S. Nakanishi, R. Kageyama, Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements. Journal of Biological Chemistry. ,vol. 269, pp. 5150- 5156 ,(1994) , 10.1016/S0021-9258(17)37668-8
J. Moscoso del Prado, A. Garcia-Bellido, Genetic regulation of the Achaete-scute complex of Drosophila melanogaster Wilhelm Roux's Archives of Developmental Biology. ,vol. 193, pp. 242- 245 ,(1984) , 10.1007/BF01260345
M. Ishibashi, K. Moriyoshi, Y. Sasai, K. Shiota, S. Nakanishi, R. Kageyama, Persistent expression of helix‐loop‐helix factor HES‐1 prevents mammalian neural differentiation in the central nervous system. The EMBO Journal. ,vol. 13, pp. 1799- 1805 ,(1994) , 10.1002/J.1460-2075.1994.TB06448.X
Kiyomitsu Miyachi, Marvin J Fritzler, Eng M Tan, None, Autoantibody to a Nuclear Antigen in Proliferating Cells Journal of Immunology. ,vol. 121, pp. 2228- 2234 ,(1978)
G. Weinmaster, G. Lemke, V.J. Roberts, A homolog of Drosophila Notch expressed during mammalian development Development. ,vol. 113, pp. 199- 205 ,(1991) , 10.1242/DEV.113.1.199
P.J. Swiatek, T. Gridley, A.P. McMahon, R.J. Greenspan, F.F. Del Amo, D.E. Smith, M. Gendron-Maguire, Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development. ,vol. 115, pp. 737- 744 ,(1992) , 10.1242/DEV.115.3.737
S CAMPUZANO, J MODOLELL, Patterning of the Drosophila nervous system: the achaete-scute gene complex. Trends in Genetics. ,vol. 8, pp. 202- 208 ,(1992) , 10.1016/0168-9525(92)90234-U
Louvenia D. Carter-Dawson, Matthew M. Lavail, Rods and cones in the mouse retina. II. Autoradiographic analysis of cell generation using tritiated thymidine The Journal of Comparative Neurology. ,vol. 188, pp. 263- 272 ,(1979) , 10.1002/CNE.901880205
J. Lee, S. Hollenberg, L Snider, D. Turner, N Lipnick, H Weintraub, Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein Science. ,vol. 268, pp. 836- 844 ,(1995) , 10.1126/SCIENCE.7754368