Sp1 participates in the cadmium-induced imbalance of the placental glucocorticoid barrier by suppressing 11β-HSD2 expression.

作者: Fengyun Fan , Wanting Shen , Sisi Wu , Na Chen , Xia Tong

DOI: 10.1016/J.ENVPOL.2020.113976

关键词: PromoterOffspringFetusGlucocorticoidGestationPlacentaCorticosteroneAndrologyTrophoblastChemistry

摘要: Cadmium (Cd) is widely present in the environment as a heavy metal poison. Prenatal Cd exposure can damage the placental glucocorticoid barrier, leading to foetal growth restriction (…

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