Relationship between Numbers of Cortical Argentophilic and Congophilic Senile Plaques in the Brains of Elderly People with and without Senile Dementia of Alzheimer Type

作者: Peter H. Gibson

DOI: 10.1159/000212716

关键词: Senile dementiaDegenerative diseaseAlzheimer's diseasePathogenesisMedicineSilver stainPathologyElderly peopleSenile plaquesAmyloid

摘要: Four neocortical regions (frontal, parietal, temporal, occipital) of 44 cases were impregnated by a silver stain to show neuritic plaques and stained with Congo red amyloid plaques. In 11 large numbers argentophilic these decreased significantly age while the reverse appeared be true for congophilic remaining 34 which had few increased in parietal occipital regions. These results suggest that component senile precedes cores their pathogenesis although causative relationship is not implied.

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