Proteins in cerebrospinal fluid and plasma of postnatal Monodelphis domestica (grey short-tailed opossum).
作者： K.M. Dziegielewska , M. Habgood , S.E. Jones , M. Reader , N.R. Saunders
DOI: 10.1016/0305-0491(89)90133-8
关键词: Biology 、 Extracellular 、 Blood plasma 、 alpha-2-Macroglobulin 、 Blood proteins 、 CSF albumin 、 Internal medicine 、 Albumin 、 Endocrinology 、 Monodelphis domestica 、 Cerebrospinal fluid
摘要: Abstract 1. The protein composition and concentrations of total in cerebrospinal fluid (CSF) plasma opossum ( Monodelphis domestica ) from birth until adulthood have been estimated. 2. Total CSF increased to a peak concentration between 5 10 days (500 mg/100 ml) after which it declined rapidly. 3. started at low level (below 400 progressively the adult value (8500 ml). 4. Proteins identified were: albumin, alpha 1 antitrypsin, transferrin, 2 macroglobulin, lipoproteins immunoglobulin G. A fetal protein, probably alpha-fetoprotein, has identified. 5. only proteins found within brain, even very immature newborn this species, appeared an intracellular rather than extracellular distribution. This indicates that blood-brain barrier is present early development there also CSF-brain appears exclude brain space.
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