Crypts are the site of intestinal fluid and electrolyte secretion
作者： M. Welsh , P. Smith , M Fromm , R. Frizzell
关键词: Secretagogue 、 Adenosine 、 Crypt 、 Biology 、 Electrolyte 、 Cell biology 、 Biochemistry 、 Large intestine 、 Secretion 、 Duct (anatomy) 、 Membrane potential
摘要: The site of adenosine 3',5'-monophosphate-mediated fluid and electrolyte secretion across mammalian large intestine was found to be the crypts Lieberkuhn by means two techniques. First, formation droplets visualized on oil-covered mucosal surface directly over crypt duct openings when stimulated. Second, microelectrode impalement individual cells revealed that only produced a pattern secretagogue induced alterations in membrane potential resistance characteristic secretory epithelia.
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