Modern adjuvants do not enhance the efficacy of an inactivated African swine fever virus vaccine preparation.

作者: Sandra Blome , Claudia Gabriel , Martin Beer

DOI: 10.1016/J.VACCINE.2014.05.051

关键词: VirologyInactivated vaccineAntibodyAntibody-dependent enhancementClinical courseVirulenceVirusImmunizationAfrican swine fever virusImmunologyMedicine

摘要: … In conclusion, the selected modern adjuvants did not enhance the efficacy of BEI-inactivated African swine fever virus vaccines. Although ASFV-specific antibodies were present in all …

参考文章(18)
J. M. Sánchez-Vizcaíno, L. Mur, B. Martínez-López, African swine fever: an epidemiological update. Transboundary and Emerging Diseases. ,vol. 59, pp. 27- 35 ,(2012) , 10.1111/J.1865-1682.2011.01293.X
Angel L. Carrascosa, M. Jose Bustos, Patricia Leon, Methods for growing and titrating African swine fever virus: field and laboratory samples. Current protocols in pharmacology. ,vol. 53, ,(2011) , 10.1002/0471143030.CB2614S53
Donald P King, Scott M Reid, Geoffrey H Hutchings, Sylvia S Grierson, Philip J Wilkinson, Linda K Dixon, Armanda D.S Bastos, Trevor W Drew, Development of a TaqMan® PCR assay with internal amplification control for the detection of African swine fever virus Journal of Virological Methods. ,vol. 107, pp. 53- 61 ,(2003) , 10.1016/S0166-0934(02)00189-1
F. Milián-Suazo, J.A. Gutiérrez-Pabello, L. Bojorquez-Narváez, A.M. Anaya-Escalera, G.J. Cantó-Alarcón, J.L. González-Enríquez, J. Campos-Guillén, IFN-g response to vaccination against tuberculosis in dairy heifers under commercial settings. Research in Veterinary Science. ,vol. 90, pp. 419- 424 ,(2011) , 10.1016/J.RVSC.2010.07.018
José Manuel Sánchez-Vizcaíno, Lina Mur, Beatriz Martínez-López, African swine fever (ASF): five years around Europe. Veterinary Microbiology. ,vol. 165, pp. 45- 50 ,(2013) , 10.1016/J.VETMIC.2012.11.030
A.G Andrianarivo, L Choromanski, S.P McDonough, A.E Packham, P.A Conrad, Immunogenicity of a killed whole Neospora caninum tachyzoite preparation formulated with different adjuvants International Journal for Parasitology. ,vol. 29, pp. 1613- 1625 ,(1999) , 10.1016/S0020-7519(99)00116-2
Raquel Portugal, Alexandre Leitão, Carlos Martins, Characterization of African swine fever virus IAP homologue expression in porcine macrophages infected with different virulence isolates. Veterinary Microbiology. ,vol. 139, pp. 140- 146 ,(2009) , 10.1016/J.VETMIC.2009.04.030
Chris AL Oura, MS Denyer, H Takamatsu, RME Parkhouse, In vivo depletion of CD8+ T lymphocytes abrogates protective immunity to African swine fever virus. Journal of General Virology. ,vol. 86, pp. 2445- 2450 ,(2005) , 10.1099/VIR.0.81038-0
Raquel Portugal, Alexandre Leitão, Carlos Martins, Apoptosis in porcine macrophages infected in vitro with African swine fever virus (ASFV) strains with different virulence Archives of Virology. ,vol. 154, pp. 1441- 1450 ,(2009) , 10.1007/S00705-009-0466-X