Cinnamaldehyde up-regulates the mRNA expression level of TRPV1 receptor potential ion channel protein and its function in primary rat DRG neurons in vitro.
作者： Feng Sui , Na Lin , Jian-You Guo , Chang-Bin Zhang , Xin-Liang Du
DOI: 10.1080/10286020903451732
关键词: Capsaicin 、 TRPV1 、 Endocrinology 、 Gene expression 、 TRPM8 、 Neuron 、 Cell biology 、 Ion channel 、 Internal medicine 、 Mechanism of action 、 Chemistry 、 Transient receptor potential channel
摘要: … mRNA expression levels and functions of both TRPV1 and TRPM8. The results showed … TRPV1 at both 37 and 39C, and its calcium-mediating function was significantly increased at 39C…
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sci-hub.se 参考文章(22)
Michael J. Caterina, Mark A. Schumacher, Makoto Tominaga, Tobias A. Rosen, Jon D. Levine, David Julius, The capsaicin receptor: a heat-activated ion channel in the pain pathway Nature. ,vol. 389, pp. 816- 824 ,(1997) , 10.1038/39807
Ardem Patapoutian, Andrea M. Peier, Gina M. Story, Veena Viswanath, ThermoTRP channels and beyond: mechanisms of temperature sensation Nature Reviews Neuroscience. ,vol. 4, pp. 529- 539 ,(2003) , 10.1038/NRN1141
Sivakumar J. T. Gowder, H. Devaraj, Effect of the food flavour cinnamaldehyde on the antioxidant status of rat kidney. Basic & Clinical Pharmacology & Toxicology. ,vol. 99, pp. 379- 382 ,(2006) , 10.1111/J.1742-7843.2006.PTO_560.X
Jiehong Huang, Xuming Zhang, Peter A. McNaughton, Modulation of temperature-sensitive TRP channels. Seminars in Cell & Developmental Biology. ,vol. 17, pp. 638- 645 ,(2006) , 10.1016/J.SEMCDB.2006.11.002
Z. Szelenyi, Z. Hummel, J. Szolcsanyi, J. B. Davis, Daily body temperature rhythm and heat tolerance in TRPV1 knockout and capsaicin pretreated mice. European Journal of Neuroscience. ,vol. 19, pp. 1421- 1424 ,(2004) , 10.1111/J.1460-9568.2004.03221.X
David D. McKemy, Werner M. Neuhausser, David Julius, Identification of a cold receptor reveals a general role for TRP channels in thermosensation Nature. ,vol. 416, pp. 52- 58 ,(2002) , 10.1038/NATURE719
Yue-Ying Ma, Hai-Ru Huo, Cang-Hai Li, Bao-Sheng Zhao, Lan-Fang Li, Feng Sui, Shu-Ying Guo, Ting-Liang Jiang, Effects of Cinnamaldehyde on PGE2 Release and TRPV4 Expression in Mouse Cerebral Microvascular Endothelial Cells Induced by Interleukin-1β Biological & Pharmaceutical Bulletin. ,vol. 31, pp. 426- 430 ,(2008) , 10.1248/BPB.31.426
Tetsuro Hori, Capsaicin and central control of thermoregulation Pharmacology & Therapeutics. ,vol. 26, pp. 389- 416 ,(1984) , 10.1016/0163-7258(84)90041-X
Tohko Iida, Isao Shimizu, Michele L. Nealen, Ashley Campbell, Michael Caterina, Attenuated fever response in mice lacking TRPV1 Neuroscience Letters. ,vol. 378, pp. 28- 33 ,(2005) , 10.1016/J.NEULET.2004.12.007
Michael J Caterina, Anderas Leffler, Annika B Malmberg, William J Martin, Jodie Trafton, KR Petersen-Zeitz, M Koltzenburg, Alan I Basbaum, David Julius, Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor Science. ,vol. 288, pp. 306- 313 ,(2000) , 10.1126/SCIENCE.288.5464.306