Assays for angiogenesis: a review.

作者: Robert Auerbach , Wanda Auerbach , Igor Polakowski

DOI: 10.1016/0163-7258(91)90038-N

关键词: VasculogenesisPathologyAngiogenesisTumor growthBlood vesselCancer researchDiabetic retinopathyWound healingDiseaseIn vivoMedicine

摘要: Accurate, reliable quantitation of the neovascular (angiogenic) response, both in vitro and vivo, is an essential requirement for study new blood vessel growth. Over many years, ingenious ways have been developed measuring this process, they contributed much to our present understanding vasculogenesis angiogenesis that accompany normal embryonic development, lactation wound healing, as well tumor growth a variety other disease states ranging from diabetic retinopathy autoimmune vasculitis. In review we describe evaluate methodology specific features some most frequently used these assays.

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