Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia
作者： LanLan Shen , Minoru Toyota , Yutaka Kondo , Toshiro Obata , Sophia Daniel
DOI: 10.1182/BLOOD-2002-08-2466
关键词: DNA methylation 、 Cell cycle 、 Methylation 、 Gene 、 Acute lymphocytic leukemia 、 Biology 、 Gene silencing 、 Cancer 、 Philadelphia chromosome 、 Immunology 、 Cancer research
摘要: … start site of p57KIP2 was found in acute lymphocytic leukemia (ALL)–derived cell lines. Methylation of this region correlated with gene silencing, and treatment of methylated/silenced …
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