Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase
作者： S. L. Bullock , J. M. Fletcher , R. S.P. Beddington , V. A. Wilson
关键词: Ureteric bud 、 Biology 、 Perlecan 、 Fibroblast growth factor 、 Heparan sulfate 、 Molecular biology 、 Gene expression 、 Heparan Sulfate Biosynthesis 、 Mutant 、 Kidney development
摘要: … Given the recessive nature of the Hs2stmutant phenotype (see below) the gene trap insertion is likely to cause a loss-of-function mutation; however, we cannot state categorically that it …
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