Atypical manifestations of tegumentary leishmaniasis in a transmission area of Leishmania braziliensis in the state of Bahia, Brazil

作者: L.H. Guimarães , P.R.L. Machado , E.L. Lago , D.J. Morgan , A. Schriefer

DOI: 10.1016/J.TRSTMH.2009.04.019

关键词: DermatologyTropical medicineImmunologyAmphotericin BCohortComorbidityLeishmania braziliensisCutaneous leishmaniasisMedicinePharmacotherapyLeishmaniasis

摘要: American tegumentary leishmaniasis (ATL) can occur in different forms, classically categorized as cutaneous (CL), mucosal (ML), diffuse and disseminated leishmaniasis. Atypical ATL have been described sporadic case reports. In this study we analyzed the presence of atypical manifestations (vegetative, verrucous, crusted lupoid) among a cohort all patients presenting to Health Post Corte de Pedra. Among 1396 diagnosed with 2005–06, 35 (2.5%) presented disease. Of these patients, 14 were pregnant women, 2 co-infected HIV, 19 had no comorbidity or other apparent risk factors for development ATL. These focus study. They predominantly adult males, frequently facial lesions (p< 0.001 OR=17.5 CI 95% 6.1 – 52.4) higher rates treatment failure antimony therapy OR= 327 45 6668) when compared classic attended same period.

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