PET Imaging of Response and Resistance to Cancer Therapy
作者： David A. Mankoff , Kenneth A. Krohn
DOI: 10.1007/978-1-59745-035-5_5
关键词: Cancer 、 Cancer therapy 、 Pet imaging 、 Medical physics 、 In patient 、 Medicine 、 Positron emission tomography 、 Molecular imaging 、 Targeted therapy 、 In vivo
摘要: As cancer treatment moves towards more targeted therapy, there is an increasing need for tools to guide therapy selection and evaluate response. Biochemical molecular imaging can complement existing in vitro assay methods likely play a key role early drug testing development, as well future clinical practice. Imaging ideally suited assessing the spatial temporal heterogeneity of measure vivo effects. This chapter highlights approaches focusing on positron emission tomography those that have undergone preliminary patients. Examples showing how be used (1) assess therapeutic target, (2) identify resistance factors, (3) response are described.
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