Vertical Transmission in a Two-Strain Model of Dengue Fever

作者: David Murillo , Susan A. Holechek , Anarina L. Murillo , Fabio Sanchez , Carlos Castillo-Chavez

DOI: 10.1080/23737867.2014.11414484

关键词: Dengue virusDengue outbreakTransmission (mechanics)Strain (biology)VirologyEcologyContext (language use)BiologyCompetitive exclusionDengue fever

摘要: AbstractThe role of vertical transmission in vectors has rarely been addressed the study dengue dynamics and control, part because it was not considered a critical population-level factor. In this paper, we apply pioneering modeling ideas Ross MacDonald, motivated by context 2000–2001 outbreak Peru, to assess multi-strain competition. An invading strain virus (DENV-2) from Asia rapidly circulated into Peru eventually displacing DENV-2 American. A host-dengue model that considers competing these two genotypes, resident or American type invasive more virulent Asian strain, is introduced analyzed. The incorporates potentially advantageous trait. Conditions for competitive exclusion strains are established. used show lower rates sufficient presence vert...

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