Scaling deterministic lateral displacement arrays for high throughput and dilution-free enrichment of leukocytes
作者： David W Inglis , Megan Lord , Robert E Nordon
DOI: 10.1088/0960-1317/21/5/054024
关键词: Blood product 、 Filtration 、 Biomedical engineering 、 Chromatography 、 Throughput (business) 、 Whole blood 、 Microfluidics 、 Volumetric flow rate 、 Scaling 、 Chemistry 、 Dilution
摘要: A disposable device for fractionation of blood into its components that is simple to operate and provides throughput greater than 1 mL min−1 highly sought after in medical diagnostics therapies. This paper describes a with parallel deterministic lateral displacement devices enrichment leukocytes from blood. We show capture 98% approximately ten-fold whole demonstrate scaling up through the integration six achieve flow rate 115 µL undiluted per minute atmosphere applied pressure.
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