Radiolabelling of pharmaceutical dosage forms by neutron activation of samarium‐152

作者: M B Awang , J G Hardy , S S Davis , I R Wilding , S J Parry

DOI: 10.1002/JLCR.2580331008

关键词: ChemistryNeutron captureYield (chemistry)OxideNuclear chemistryNeutron activationSamariumNatural abundanceDosage formNeutron flux

摘要: Samarium-152 can be activated in a neutron flux for the labelling of pharmaceutical dosage forms evaluation by gamma scintigraphy. The samarium is incorporated as oxide powder which available with 152Sm its natural isotopic abundance or isotopically enriched. yield 153Sm was reduced considerably following activation non-isotopically enriched oxide. This attributed to high capture 149Sm present In order keep mass added minimum and also reduce irradiation time, it recommended that should used routinely when radiolabelling forms.

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