HPLC determination of enoxacin, ciprofloxacin, norfloxacin and ofloxacin with photoinduced fluorimetric (PIF) detection and multiemission scanning: application to urine and serum.
作者： A. Espinosa-Mansilla , A. Muñoz de la Peña , D. González Gómez , F. Salinas
DOI: 10.1016/J.JCHROMB.2005.05.045
关键词: Chemistry 、 Detection limit 、 High-performance liquid chromatography 、 Enoxacin 、 Fluorescence spectrometry 、 Ofloxacin 、 Antibacterial agent 、 Chromatography 、 Norfloxacin 、 Urine
摘要: The fluorescence emission of the fluoroquinolones enoxacin (ENO), ciprofloxacin (CIPRO), norfloxacin (NOR) and ofloxacin (OFLO) notably increased by UV irradiation during few minutes, in ethanolic-water medium. An HPLC method has been developed, for determination these fluoroquinolones, based separation formed photoproducts. Optimization analytical wavelengths carried out fast multiemission scanning detection. highest sensitivity found when measuring at 407 490 nm, ENO OFLO, respectively, 444 nm both NOR CIPRO (exciting 277 nm). According to criterium Clayton, using 0.05 as false positive negative error assurance probabilities, detection limits 7.3, 6.0, 6.3 14.5 ng/mL, ENO, NOR, have found. Urine serum samples successfully analyzed, with recovery values ranging among 99-97% 98-103%, urine serum, respectively.
elsevier.com
sci-hub.se 参考文章(23)
Jason Choi, Arlene J Yee, Dianne Thompson, Jurek Samoluk, Mark Mitchell, William D Black, Determination of fluoroquinolone residues in animal tissues using Escherichia coli as indicator organism. Journal of AOAC International. ,vol. 82, pp. 1407- 1412 ,(1999) , 10.1093/JAOAC/82.6.1407
Ph Schmitt-Kopplin, J Burhenne, D Freitag, M Spiteller, A Kettrup, Development of capillary electrophoresis methods for the analysis of fluoroquinolones and application to the study of the influence of humic substances on their photodegradation in aqueous phase Journal of Chromatography A. ,vol. 837, pp. 253- 265 ,(1999) , 10.1016/S0021-9673(99)00079-5
O BALLESTEROS, I TORO, V SANZNEBOT, A NAVALON, J VILCHEZ, J BARBOSA, Determination of fluoroquinolones in human urine by liquid chromatography coupled to pneumatically assisted electrospray ionization mass spectrometry. Journal of Chromatography B. ,vol. 798, pp. 137- 144 ,(2003) , 10.1016/J.JCHROMB.2003.09.019
Luis Cuadros Rodríguez, Ana M. García Campa[nbreve]Ta, Carlos Jiménez Linares, Manuel Román Ceba, Estimation of Performance Characteristics of an Analytical Method Using the Data Set Of The Calibration Experiment Analytical Letters. ,vol. 26, pp. 1243- 1258 ,(1993) , 10.1080/00032719308019900
Sara Baldelli, Stefano Murgia, Simona Merlini, Stefania Zenoni, Norberto Perico, Giuseppe Remuzzi, Dario Cattaneo, High-performance liquid chromatography with ultraviolet detection for therapeutic drug monitoring of everolimus. Journal of Chromatography B. ,vol. 816, pp. 99- 105 ,(2005) , 10.1016/J.JCHROMB.2004.11.016
Steven C. Wallis, Bruce G. Charles, Lawrence R. Gahan, Rapid and economical high-performance liquid chromatographic method for the determination of norfloxacin in serum using a microparticulate C18 guard cartridge Journal of Chromatography B: Biomedical Sciences and Applications. ,vol. 674, pp. 306- 309 ,(1995) , 10.1016/0378-4347(95)00316-9
M. Córdoba-Borrego, M. Córdoba-Dı́az, D. Córdoba-Dı́az, Validation of a high-performance liquid chromatographic method for the determination of norfloxacin and its application to stability studies (photo-stability study of norfloxacin) Journal of Pharmaceutical and Biomedical Analysis. ,vol. 18, pp. 919- 926 ,(1999) , 10.1016/S0731-7085(98)00037-5
A Espinosa-Mansilla, A Muñoz de la Peña, F Salinas, D González Gómez, Partial least squares multicomponent fluorimetric determination of fluoroquinolones in human urine samples. Talanta. ,vol. 62, pp. 853- 860 ,(2004) , 10.1016/J.TALANTA.2003.10.037
Hoang Anh Nguyen, Jean Grellet, Boubakar B Ba, Claudine Quentin, Marie-Claude Saux, None, Simultaneous determination of levofloxacin, gatifloxacin and moxifloxacin in serum by liquid chromatography with column switching. Journal of Chromatography B. ,vol. 810, pp. 77- 83 ,(2004) , 10.1016/J.JCHROMB.2004.07.019
Giuseppe Carlucci, Analysis of fluoroquinolones in biological fluids by high-performance liquid chromatography. Journal of Chromatography A. ,vol. 812, pp. 343- 367 ,(1998) , 10.1016/S0021-9673(98)00274-X