Role of Nitric Oxide in Central Sympathetic Outflow
作者： Kaushik P. Patel , Yi-Fan Li , Yoshitaka Hirooka
DOI: 10.1177/153537020122600902
关键词: Systemic administration 、 Central nervous system 、 Nitric oxide 、 Endocrinology 、 Heart failure 、 Cardiovascular control 、 Sympathetic outflow 、 Sympathetic nervous system 、 Chemistry 、 Nitric oxide synthase 、 Internal medicine
摘要: The gaseous molecule nitric oxide (NO) plays an important role in cardiovascular homeostasis. It this by its action on both the central and peripheral autonomic nervous systems. In review, of NO regulation sympathetic outflow subsequent control is examined. After a brief introduction concerning location synthase (NOS) containing neurons system (CNS), studies that demonstrate effect systemic administration modulators will be presented. effects as assessed intracerebroventricular, intracisternal, or direct injection within specific areas also discussed. Our demonstrating medullary hypothalamic sites involved are summarized. review concluded with discussion mechanisms altered disease states such hypertension heart failure.
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