Comparison of activated charcoal and gastric lavage in the prevention of aspirin absorption

作者: Brent T. Burton , Marc J. Bayer , Lauren Barron , John P. Aitchison

DOI: 10.1016/0736-4679(84)90203-8

关键词: Absorption (skin)MedicineAnesthesiaGastric lavageAspirinPeak plasmaActivated charcoalInitial treatment

摘要: Abstract Effectiveness of initial treatment aspirin (ASA) overdosage was evaluated by comparing with activated charcoal (AC) to gastric lavage in combination AC. Dogs were used as subjects four experimental groups. All administered an overdose 500 mg/kg ASA. Treatment performed 30 minutes later on all groups except controls. AC alone resulted a 17% reduction (P . 05) peak plasma salicylate levels compared When preceded administration AC, 37%

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