Cinacalcet as adjunctive therapy for hereditary 1,25‐dihydroxyvitamin D–resistant rickets
作者： Tarak Srivastava , Uri S Alon
DOI: 10.1002/JBMR.1838
关键词: Rickets 、 Gastroenterology 、 Secondary hyperparathyroidism 、 Calcitriol receptor 、 Calcimimetic 、 Calcium 、 Calcium metabolism 、 Cinacalcet 、 Endocrinology 、 Internal medicine 、 Vitamin 、 Medicine
摘要: Secondary hyperparathyroidism from inadequate calcium absorption in the gut, is underlying pathophysiology for rachitic changes hereditary vitamin D–resistant rickets (HVDRR). We describe a novel use of Cinacalcet to treat child with HVDRR whom conventional modes therapy had be discontinued. high-dose oral effectively normalized metabolic abnormalities and bone condition. The relative ease administration calcimimetic as once- or twice-daily preparation, compared traditional intravenous administration, should encourage its move frontline treatment disorder. © 2013 American Society Bone Mineral Research.
sci-hub.se 参考文章(19)
P.J. Malloy, D. Feldman, Hereditary 1,25-Dihydroxyvitamin D-resistant rickets. Endocrine development. ,vol. 6, pp. 175- 199 ,(2003) , 10.1159/000072776
Uri S. Alon, René G. VanDeVoorde, Beneficial effect of cinacalcet in a child with familial hypocalciuric hypercalcemia. Pediatric Nephrology. ,vol. 25, pp. 1747- 1750 ,(2010) , 10.1007/S00467-010-1547-5
Uri S. Alon, Rachel Levy-Olomucki, Wayne V. Moore, Jason Stubbs, Shiguang Liu, L. Darryl Quarles, Calcimimetics as an Adjuvant Treatment for Familial Hypophosphatemic Rickets Clinical Journal of The American Society of Nephrology. ,vol. 3, pp. 658- 664 ,(2008) , 10.2215/CJN.04981107
Nina S. Ma, Peter J. Malloy, Pisit Pitukcheewanont, Daina Dreimane, Mitchell E. Geffner, David Feldman, Hereditary vitamin D resistant rickets: Identification of a novel splice site mutation in the vitamin D receptor gene and successful treatment with oral calcium therapy Bone. ,vol. 45, pp. 743- 746 ,(2009) , 10.1016/J.BONE.2009.06.003
Jutta Muscheites, Marianne Wigger, Erdmute Drueckler, Dagmar-Christiane Fischer, Guenther Kundt, Dieter Haffner, Cinacalcet for secondary hyperparathyroidism in children with end-stage renal disease Pediatric Nephrology. ,vol. 23, pp. 1823- 1829 ,(2008) , 10.1007/S00467-008-0810-5
Peter J. Malloy, Jining Wang, Tarak Srivastava, David Feldman, Hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia resulting from a novel missense mutation in the DNA-binding domain of the vitamin D receptor. Molecular Genetics and Metabolism. ,vol. 99, pp. 72- 79 ,(2010) , 10.1016/J.YMGME.2009.09.004
Zeev Hochberg, Dov Tiosano, Lea Even, Calcium therapy for calcitriol-resistant rickets. The Journal of Pediatrics. ,vol. 121, pp. 803- 808 ,(1992) , 10.1016/S0022-3476(05)81919-5
Yosef Weisman, Itay Bab, Dan Gazit, Zvi Spirer, Michael Jaffe, Zeev Hochberg, Long-term intracaval calcium infusion therapy in end-organ resistance to 1,25-dihydroxyvitamin D The American Journal of Medicine. ,vol. 83, pp. 984- 990 ,(1987) , 10.1016/0002-9343(87)90666-8
Aida Al-Aqeel, Pinar Ozand, Samia Sobki, Wafa Sewairi, Stephen Marx, The combined use of intravenous and oral calcium for the treatment of vitamin D dependent rickets type II (VDDRII). Clinical Endocrinology. ,vol. 39, pp. 229- 237 ,(1993) , 10.1111/J.1365-2265.1993.TB01779.X
Dov Tiosano, Ze’ev Hochberg, Hypophosphatemia : the common denominator of all rickets Journal of Bone and Mineral Metabolism. ,vol. 27, pp. 392- 401 ,(2009) , 10.1007/S00774-009-0079-1