The study of trypanosome species circulating in domestic animals in two human African trypanosomiasis foci of Côte d'Ivoire identifies pigs and cattle as potential reservoirs of Trypanosoma brucei gambiense

摘要: Background Important control efforts have led to a significant reduction of the prevalence human African trypanosomiasis (HAT) in Cote d’Ivoire, but disease is still present several foci. The existence an animal reservoir Trypanosoma brucei gambiense may explain persistence these foci where breeding important source income (AAT) unknown. aim this study was identify trypanosome species circulating domestic animals both Bonon and Sinfra HAT endemic foci. Methodology/Principal findings 552 (goats, pigs, cattle sheep) were included. Blood samples tested for trypanosomes by microscopic observation, species-specific PCR T. sl, congolense, vivax subspecies-specific b. immune trypanolysis (TL). Infection rates varied significantly between far highest pigs (30%). s.l most prevalent (13.7%) followed congolense. No identified while high TL positivity observed using specific variants (up 27.6% focus). Conclusion This shows that are highly infected studied This particularly true possibly due higher exposure tsetse flies. Whereas s.l. species, discordant results obtained regarding identification. It therefore crucial develop better tools epidemiological role potential gambiense. Our illustrates importance “one health” approaches reach elimination contribute AAT