Molecular characterization of chronic obstructive pulmonary disease-related non-small cell lung cancer through aberrant methylation and alterations of EGFR signaling.

作者: Makoto Suzuki , Hironobu Wada , Mitsuru Yoshino , Lei Tian , Hisayuki Shigematsu

DOI: 10.1245/S10434-009-0739-3

关键词: Pulmonary diseaseSurgical oncologyPathogenesisOncologyLung cancerEpidermal growth factor receptorMedicineCOPDInternal medicineNon small cellAberrant methylation

摘要: Background The aim of this study was to evaluate the molecular influence chronic obstructive pulmonary diseases (COPD) on pathogenesis non-small cell lung cancer (NSCLC).

参考文章(41)
Jong Park, Romulo Martin Brena, Mike Gruidl, Jun Zhou, Tim Huang, Christoph Plass, Melvyn S. Tockman, CpG island hypermethylation profiling of lung cancer using restriction landmark genomic scanning (RLGS) analysis. Cancer Biomarkers. ,vol. 1, pp. 193- 200 ,(2005) , 10.3233/CBM-2005-12-307
Makoto Suzuki, Hisayuki Shigematsu, Takao Takahashi, Narayan Shivapurkar, Ubaradka G. Sathyanarayana, Toshihiko Iizasa, Takehiko Fujisawa, Adi F. Gazdar, Aberrant methylation of Reprimo in lung cancer Lung Cancer. ,vol. 47, pp. 309- 314 ,(2005) , 10.1016/J.LUNGCAN.2004.08.006
Stephen B. Baylln, James G. Herman, Jeremy R. Graff, Paula M. Vertino, Jean-Pierre Issa, ALTERATIONS IN DNA METHYLATION : A FUNDAMENTAL ASPECT OF NEOPLASIA Advances in Cancer Research. ,vol. 72, pp. 141- 196 ,(1998) , 10.1016/S0065-230X(08)60702-2
Sabine Zöchbauer-Müller, John D. Minna, Adi F. Gazdar, Shinichi Toyooka, Arvind K. Virmani, Eugene P. Frenkel, Alfredo J. Farinas, John McConnell, Kiyomi O. Toyooka, Riichiroh Maruyama, Aberrant Promoter Methylation Profile of Prostate Cancers and Its Relationship to Clinicopathological Features Clinical Cancer Research. ,vol. 8, pp. 514- 519 ,(2002)
Yasuo Sekine, Yoshito Yamada, Masako Chiyo, Takekazu Iwata, Takahiro Nakajima, Kazuhiro Yasufuku, Makoto Suzuki, Takehiko Fujisawa, Association of Chronic Obstructive Pulmonary Disease and Tumor Recurrence in Patients With Stage IA Lung Cancer After Complete Resection The Annals of Thoracic Surgery. ,vol. 84, pp. 946- 950 ,(2007) , 10.1016/J.ATHORACSUR.2007.04.038
Yasuo Sekine, Takekazu Iwata, Masako Chiyo, Kazuhiro Yasufuku, Shinichiro Motohashi, Shigetoshi Yoshida, Makoto Suzuki, Toshihiko Iizasa, Yukio Saitoh, Takehiko Fujisawa, Minimal alteration of pulmonary function after lobectomy in lung cancer patients with chronic obstructive pulmonary disease The Annals of Thoracic Surgery. ,vol. 76, pp. 356- 361 ,(2003) , 10.1016/S0003-4975(03)00489-2
Ioanna Dialyna, Spiros Miyakis, Niki Georgatou, Demetrios Spandidos, Genetic polymorphisms of CYP1A1, GSTM1 and GSTT1 genes and lung cancer risk Oncology Reports. ,vol. 10, pp. 1829- 1835 ,(2003) , 10.3892/OR.10.6.1829
Changsong Zhang, Zhengyou Li, Yue Cheng, Fengqi Jia, Rong Li, Mengchao Wu, Ke Li, Lixin Wei, CpG Island Methylator Phenotype Association with Elevated Serum α-Fetoprotein Level in Hepatocellular Carcinoma Clinical Cancer Research. ,vol. 13, pp. 944- 952 ,(2007) , 10.1158/1078-0432.CCR-06-2268
A Sano, H Kage, K Sugimoto, H Kitagawa, N Aki, A Goto, M Fukayama, J Nakajima, S Takamoto, T Nagase, Y Yatomi, N Ohishi, D Takai, A second-generation profiling system for quantitative methylation analysis of multiple gene promoters: application to lung cancer. Oncogene. ,vol. 26, pp. 6518- 6525 ,(2007) , 10.1038/SJ.ONC.1210483
Makoto Suzuki, Toshihiko Iizasa, Takahiro Nakajima, Rieko Kubo, Akira Iyoda, Kenzo Hiroshima, Yukio Nakatani, Takehiko Fujisawa, Aberrant Methylation of IL-12Rβ2 Gene in Lung Adenocarcinoma Cells Is Associated with Unfavorable Prognosis Annals of Surgical Oncology. ,vol. 14, pp. 2636- 2642 ,(2007) , 10.1245/S10434-006-9310-7