Disrupted neural responses to phonological and orthographic processing in dyslexic children: an fMRI study.

作者: Elise Temple , Russell A. Poldrack , Joanna Salidis , Gayle K. Deutsch , Paula Tallal

DOI: 10.1097/00001756-200102120-00024

关键词: PhonologyCortex (anatomy)Parietal lobeCognitive psychologyReading (process)Temporal lobeLanguage disorderPsychologyDyslexiaExtrastriate cortex

摘要: Developmental dyslexia, characterized by difficulty in reading, has been associated with phonological and orthographic processing deficits. fMRI was performed on dyslexic normal-reading children (8‐12 years old) during tasks of rhyming matching visually presented letter pairs. During rhyming, both normal reading had activity left frontal brain regions, whereas only temporo-parietal cortex. matching, normalreading showed throughout extrastriate cortex, especially occipito-parietal little cortex this task. These results indicate dyslexia may be childhood disruptions the neural bases processes important for reading. NeuroReport 12:299‐307 & 2001 Lippincott Williams Wilkins.

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