Towards a world free from HIV and AIDS

作者: J. Albert , F. Chiodi

DOI: 10.1111/J.1365-2796.2011.02453.X

关键词: Rare diseaseMedicineAcquired immunodeficiency syndrome (AIDS)Immune systemPneumoniaVirusLymph node biopsyIsolation (health care)VirologyHuman immunodeficiency virus (HIV)

摘要: Approximately 30 years ago, in June 1981, it was reported from theCenter forDiseaseControl andPrevention (CDC) that five, otherwise healthy, homosexual men California had presented with pneumonia caused by Pneumocystis jiroveci pneumonia, a rare disease seen exclusively individualswith severely suppressed immune system. Several reports confirmed the initial observation and lent support to possibility new sexually transmitted, infectious agent circulating within gay community United States. The clinical condition named acquired immunodeficiency syndrome (AIDS). Two later, research team at Institut Pasteur under guidance of Francoise Barre-Sinoussi Luc Montagnier isolated human virus (HIV), causative AIDS, lymph node biopsy French patient. isolation characterization HIV paved way for design diagnosticmethods identify blood andbloodproducts towards development novel antiretroviral treatment (ART) control replication infected patients. For their discoveries, were awarded Nobel Prize Physiology Medicine 2008.

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