Mg2+ efflux is accomplished by an amiloride-sensitive Na+/Mg2+ antiport
作者： T. Günther , J. Vormann
DOI: 10.1016/0006-291X(85)90450-4
关键词: Efflux 、 Extracellular 、 Intracellular 、 Sodium–hydrogen antiporter 、 Antiporters 、 Amiloride 、 Kinetics 、 Antiporter 、 Biochemistry 、 Chemistry
摘要: Mg2+ efflux from Mg2+-preloaded chicken erythrocytes is caused by an electroneutral Na+/Mg2+ antiport. It depends specifically on extracellular Na+, according to Michaelis-Menten kinetics (Km = 25 mM), and reversibly noncompetitively inhibited amiloride (Ki 0.59 mM). In contrast Na+/H+ antiport, Li+, Ca2+ N-ethylmaleimide do not interfere with The antiport driven the intracellular/extracellular gradient.
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