Ion Channel Expression in Glial Cells from Trout Central Nervous System

摘要: Macroglial cells in the vertebrate gray matter are divided into two subtypes, nonmyelinating astrocytes and myelinating oligodendrocytes. To a variety of functional roles have been ascribed including nutrition neurons, uptake amino acid neurotransmitters, contribution to extracellular potassium regulation. Furthermore, electrophysiological studies revealed an astonishing repertoire voltage-dependent ligand-activated ion channels cultured as well vivo, not unlike those found neurons (5). Oligodendrocytes, on other hand, which enwrap axons with electrically insulating membrane sheath, were originally considered electrophysiologically inactive elements. Recent patch clamp studies, however, shown characteristic pattern ionic currents this cell type, too.