Detection and utilisation of quantitative trait loci in dairy cattle

摘要: The focus of the thesis is on detection quantitative trait loci (QTL) in dairy cattle and their utilisation breeding programmes. Analysis one bovine chromosome for milk production traits described a QTL protein percent was identified that significant at 1% level. When analysing it observed degree precision estimating location size (or variance) poor. Through stochastic simulation, effect incorrect parameter estimates locus effect, position genetic response from marker assisted selection investigated. From this study concluded studies should be undertaken to verify enable optimal use selection. Strategies confirm existence genome scan are outlined. Also through simulation reducing flanking-marker bracket found increase Simulation used estimate improvements rate gain two scenarios, current situation futuristic setting. with some 5% potential 30% level variance being disequilibrium alleles. general discussion addresses significance levels detection, experimental designs identify further New Zealand industry, possible future application