Nonlinearly additive forces in multivalent ligand binding to a single protein revealed with force spectroscopy.
作者： Timothy V. Ratto , Robert E. Rudd , Kevin C. Langry , Rodney L. Balhorn , Michael W. McElfresh
DOI: 10.1021/LA052087D
关键词: Polymer architecture 、 Substrate (chemistry) 、 Work (thermodynamics) 、 Biophysics 、 Force spectroscopy 、 Chemistry 、 Stereochemistry 、 Liaison 、 Polymer 、 Loading rate 、 Molecule
摘要: We present evidence of multivalent interactions between a single protein molecule and multiple carbohydrates at a pH where the protein can bind four ligands. The evidence is based …
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