Prevalence of and factors associated with sarcopenia in elderly patients with end-stage renal disease.
作者： Jwa-Kyung Kim , Sun Ryoung Choi , Myung Jin Choi , Sung Gyun Kim , Young Ki Lee
DOI: 10.1016/J.CLNU.2013.04.002
关键词: Disease 、 End stage renal disease 、 Medicine 、 Depression (differential diagnoses) 、 Cross-sectional study 、 Diabetes mellitus 、 Body mass index 、 Odds ratio 、 Sarcopenia 、 Internal medicine 、 Physical therapy
摘要: Summary Background & aims We investigated the prevalence of sarcopenia in elderly patients with end-stage renal disease (ESRD) and its relationship various markers nutrition, cognitive function, depressive symptoms, inflammation β2-microglobulin. Methods A cross-sectional study was conducted 95 having ESRD aged over 50 years. Sarcopenia defined as a decline both muscle mass strength. Results The mean age 63.9 ± 10.0 years; 56.8% were men 52.6% had diabetes. highly prevalent (37.0% 29.3% women). Subjective Global Assessment (SGA), inflammatory β2-microglobulin levels significantly associated sarcopenia, even after adjustment for age, gender, diabetes, body index. Additionally, symptoms showed higher risk relative to those without (odds ratio, OR = 6.87, 95% confidence interval, CI = 2.06–22.96) more likely be present mild dysfunction (OR = 6.35, CI = 1.62–34.96). Conclusions is closely SGA, markers, β2-microglobulin, depression dysfunction.
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