Family resemblance for serum uric acid in a Jerusalem sample of families.

摘要: Familial aggregation of serum uric acid was studied in a sample families examined the Jerusalem Lipid Research Clinic. We first homogeneity familial correlations across major origin groups Israeli population sample. In general were homogeneous groups, except for spouse pairs. Pooled among biological relatives all statistically significant. Spouse correlation upon adjustment concomitant variables moderately positive (r=0.115), yet significantly different from zero. Genetic and cultural determinants estimated utilizing path model with 10 parameters to be total 16 correlations. Under reduced model, genetic heritability (h2) 0.47±0.05 (c2) 0.11±0.03. However, our data gave suggestive evidence that higher parents (c2=0.28) than children (c2=0.10). Commingling analysis segregation also performed, findings imply there is no gene high levels segregating families.