Keeping dry and crossing membranes.
作者： Ariel Fernández
DOI: 10.1038/NBT0904-1081
关键词: Biophysics 、 Glucagon 、 Chromosomal translocation 、 Membrane 、 Chemistry
摘要: … hydrogen bonds, should be 'kept dry' if the structure is to prevail… surface are naturally designed to be dry in water. When water … of a gaslike layer (drying) through capillary evaporation 9 . …
nature.com
sci-hub.se 参考文章(20)
Mark A. Roseman, Hydrophobicity of the peptide CO···HN hydrogen-bonded group Journal of Molecular Biology. ,vol. 201, pp. 621- 623 ,(1988) , 10.1016/0022-2836(88)90642-0
Anne-Marie Sapse, Robert Rothchild, Duli C. Jain, Cecilia G. Unson, The Role of Salt Bridge Formation in Glucagon: An Experimental and Theoretical Study of Glucagon Analogs and Peptide Fragments of Glucagon Molecular Medicine. ,vol. 8, pp. 251- 262 ,(2002) , 10.1007/BF03402151
Robert A. Baughman, Andrea Leone‐Bay, Masahiko Sato, Duncan Paton, Ann H. Hunt, Donald Sarubbi, Monica Carozza, James Chou, James McDonough, Oral Delivery of Biologically Active Parathyroid Hormone Pharmaceutical Research. ,vol. 18, pp. 964- 970 ,(2001) , 10.1023/A:1010936227570
Michael Goldberg, Isabel Gomez-Orellana, Challenges for the oral delivery of macromolecules. Nature Reviews Drug Discovery. ,vol. 2, pp. 289- 295 ,(2003) , 10.1038/NRD1067
C. G. Unson, R. B. Merrifield, Identification of an essential serine residue in glucagon: implication for an active site triad. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 454- 458 ,(1994) , 10.1073/PNAS.91.2.454
A. Fernandez, R. Scott, R. S. Berry, The nonconserved wrapping of conserved protein folds reveals a trend toward increasing connectivity in proteomic networks Proceedings of the National Academy of Sciences of the United States of America. ,vol. 101, pp. 2823- 2827 ,(2004) , 10.1073/PNAS.0308295100
Ariel Fernández, Tobin R. Sosnick, Andrés Colubri, Dynamics of hydrogen bond desolvation in protein folding. Journal of Molecular Biology. ,vol. 321, pp. 659- 675 ,(2002) , 10.1016/S0022-2836(02)00679-4
Ariel Fernández, Ridgway Scott, Dehydron: a structurally encoded signal for protein interaction. Biophysical Journal. ,vol. 85, pp. 1914- 1928 ,(2003) , 10.1016/S0006-3495(03)74619-0
G. Hummer, J. C. Rasaiah, J. P. Noworyta, Water conduction through the hydrophobic channel of a carbon nanotube Nature. ,vol. 414, pp. 188- 190 ,(2001) , 10.1038/35102535
Ariel Fernández, What caliber pore is like a pipe? Nanotubes as modulators of ionic gradients Journal of Chemical Physics. ,vol. 119, pp. 5315- 5319 ,(2003) , 10.1063/1.1606439