Deep Hypothermic Low Flow Cardiopulmonary Bypass in Small Dogs

摘要: Objective— To evaluate the feasibility of and morbidity mortality associated with cardiopulmonary bypass (CPB) using deep hypothermia low flow perfusion in adult dogs weighing less than 10 kg. Study Design— Prospective, descriptive study. Animals— Two groups three underwent CPB. Group 1 (15 to 18°C), 45 minutes (20 mL/kg/min) hour aortic cross clamp time. In group 2, ultrafiltration perfusate before discontinuation was added standard treatment. Complete blood counts, serum biochemistry, urine output, ejection fraction, cardiac output were monitored for 7 days after surgery. Results— All successfully weaned from bypass. Four six survived, without major complications. One dog developed recovered septic pleuritis. died or eudianatized surgery because respiratory gastrointestinal Minor complications included anemia, hypoproteinemia, electrolyte disturbances. Transfusion requirements edema formation reduced by ultrafiltration. Conclusions— The observations this study support hypothermic Meticulous tissue handling, precise equipment, ultrafiltration, aggressive postoperative potassium supplementation are recommended smaller patients. Clinical Relevance— Increased sensitivity adverse sequelae CPB may be small patient size. Further evaluation is necessary routine clinical application tMs population.