Targeted Therapy of the Epidermal Growth Factor Receptor in the Treatment of Pancreatic Cancer
作者： Steffen Heeger
DOI: 10.1007/978-3-540-71279-4_15
关键词: Erlotinib 、 Epidermal growth factor receptor 、 Oncology 、 Cancer 、 CA19-9 、 Targeted therapy 、 Adenocarcinoma of the lung 、 Cetuximab 、 Medicine 、 Pancreatic cancer 、 Internal medicine
摘要: The epidermal growth factor receptor (EGFR)-mediated pathway is one of the most promising targets for development new strategies in anticancer treatments. so-called "small molecule" tyrosine kinase inhibitor erlotinib has gained marketing authorization United States advanced adenocarcinoma lung and pancreatic cancer, whereas antibody cetuximab registered metastatic colorectal cancer cancers head neck. Ongoing studies are evaluating impact EGFR-targeting therapy treatment locally cancer.
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